The American Association of Endocrine Surgeons, Patient Education Site

Primary hyperaldosteronism (Conn's syndrome or aldosterone-producing adrenal tumor)

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Treatment

The best treatment for primary hyperaldosteronismPrimary hyperaldosteronism - a disease where too much aldosterone is being made depends on the cause of the disease. Patients with unilateral disease should have an adrenalectomyAdrenalectomy - an operation to remove the adrenal gland. The operation usually is performed using minimally invasive techniques (i.e. laparoscopic surgery), but may require a traditional operation in cases of large, difficult to remove tumors. (See How is adrenal surgery performed?) Patients with primary hyperaldosteronism caused by bilateral adrenal hyperplasia are treated with medications (i.e. aldosterone-antagonists) that control high blood pressure and normalize levels of sodium, potassium, and water in the blood. A low-salt diet also is recommended. Please see figure 3 for an algorithm of diagnosis and treatment of primary hyperaldosteronism.

Patients with primary hyperaldosteronism who do nothing are at risk of developing the complications associated with untreated high blood pressure. These complications include heart attack and heart failure, kidney damage and kidney failure, and stroke. Patients with suspected primary hyperaldosteronism should seek proper diagnosis and treatment to avoid these harmful complications.

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