Incidence and Risk Factors

Risk Factor

In primary hyperparathyroidism, one or more of the parathyroid glands produces PTH in excess with some degree of autonomy from the regular negative feedback loop inhibition (i.e. the thermostat remains on despite the temperature being high).  In[AH1]  more than 80% of cases, a single gland is the source of excess PTH.  These are termed single adenomas.  In…

Read More

Parathyroid Function

Closeup of human pelvis bone of an anatomical human body skeleton standing in empty hospital office

The parathyroid glands are located in the neck immediately adjacent, on or even rarely within the thyroid.  Each parathyroid gland is approximately 3x4x5 millimeters and typically weighs 25-40 milligrams. Parathyroid glands produce the peptide hormone PTH, which plays a crucial role in calcium homeostasis. There are typically four parathyroid glands (a superior and inferior gland on each side…

Read More